Monday, December 29, 2008

Medical Eponyms Letter V

407. Van der Woude syndrome is an AD condition in which lip pits are seen in all gene carriers but only some individuals have cleft lips with or without cleft palate owing to variable expressivity.
408. Van Wyk-Grumbach syndrome is primary hypothyroidism associated with precocious puberty and galactorrhea.
409. Vater - ampulla is location where common bile duct enters the duodenum; described by German anatomist Vater (1684-1751).
410. Vater - ampulla is location where common bile duct enters the duodenum; described by German anatomist Vater (1684-1751).
411. Vincent’s infection is acute necrotizing ulcerative gingivitis - occurring in patients with decreased resistance to infection - from concurrent infection with the symbiotic bacteria Fusobacterium fusiforme and Borrelia vincentii.
412. Virchow’s node is supraclavicular adenopathy associated with a malignancy - often on left side - associated with stomach cancer among other neoplasms but also GI and pelvic malignancies in general. First described by Virchow in 1848 - more cases added by Troisier in 1886; referred to as Troisier’s node in France.
413. Voight - lines of is boundaries which delimit distribution area of main cutaneous nerves; seen in black and Asian skin and rarely in white subjects.
414. Volkmann contracture is sequelae of compartment syndrome post-supracondylar fracture of humerus dut to brachial artery compression where there is contraction of forearm flexors.
415. Von Braun-Fernwald’s sign is Piskacek’s sign.
416. Von Graefe sign is in Graves’s disease - lag of the upper eyelid as it follows the rotation of the eyeball downward.
417. Von Meyenburg complexes is close to or within portal tracts - small clusters of modestly dilated bile ducts embedded in a fibrous - sometimes hyalinized stroma; contain inspissated bile concrements and may communicate with the biliary tree; common and usually without clinical significance.
418. Von Recklinghausen’s disease is generalized neurofibromatosis.
419. Von Willebrand factor is vWF bridges collagen and platelets and favors platelet aggregation - ensuring platelet and vessel wall interactions; glycoprotein Ib-IX major receptor for vWF; vWF also serves as carrier for factor VIII; made in endothelial cells and megakaryocytes.
420. Von Willebrand’s disease is deficiency in von Willebrand factor; frequency of 1% - most common inherited disorder of bleeding; type 1 and 3 reduced quantity of vWF; type 2 qualitative defects in vWF.Kussmaul’s respiration is hyperpnea - associated with acidosis - especially DKA but also in uremia.

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