Thursday, January 15, 2009

CNS and Neurons

CNS and Neurons..........go through these useful points.


(CNS) contains about 10(raised to)11 (100 billion) neurons. It also contains 10–50 times this number of glial cells.

Protein Zero (P0) responsible for compaction of myelin, mutations of protein zero causes peripheral neuropathy. Nodes of Ranvier are 1micro meter in size placed 1 mm apart.

Slowly rising currents fail to fire the nerve because the nerve adapts to the applied stimulus, a process called accommodation.

Anelectrotonic-hyperpolarizing potential change, catelectrotonic- depolarizing potential change.

Absolute refractory period, corresponding to the period from the time the firing level is reached until repolarization is about one-third complete.

A decrease in extracellular Ca2+ concentration increases the excitability of nerve and muscle cells by decreasing the amount of depolarization necessary to initiate the changes in the Na+ and K+ conductance that produce the action potential.

Erlanger and Gasser Classification of Nerve Fibers into A, B, and C groups, further subdividing the A group into alpha, beta, gamma and delta fibers.

Maximum speed of construction A-delta fibers, maximum size for A-delta fibers.

Which are preganglionic autonomic fibers? Ans: Type B fibers.

A and B fibers are myelinated; C fibers are unmyelinated.

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