Monday, February 16, 2009

Few points regarding CARBAMAZEPINE

* Not an analgesic, but DOC for one of the most painful conditions.

* Acts by interrupting temporal summation of afferent impulses by a selective action on high frequency nerve impulses.

* Carbamazepine has become the drug of choice for Trigeminal Neuralgia and Partial Seizures.

* Induces it's own metabolism

* MC dose related side effect of Carbamazepine : Diplopia and Ataxia.

* Can cause idiosyncratic Aplastic Anemia and Agranulocytosis.

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