Lipoid proteinosis is a very rare genodermatosis characterized by hoarseness, skin infiltration and thickening, beaded papules on eyelid margins, and facial acneiform or pock-like scars.
Histological examinations show an extracellular PAS-positive hyaline material.
The disorder is attributed to a mutation of the extracellular-matrix protein-1 located on chromosome 1q21.
Read more at : http://www.medscape.com/viewarticle/585234_2
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