Wednesday, April 1, 2009

Table: New Pharmacological Drug Classes Introduced in 2008



Pharmacologic Class
First to be Marketed in the U.S.

FDA Approved Indication

C1 inhibitor
C1 inhibitor(CinryzeR)
Routine prophylaxis against angioedema attacks in patients with hereditary angioedema


CXCR4 chemokine receptor inhibitor
plerixa (MozobilR)
Mobilization of granulocyte-colony stimulating factor induced hematopoietic stem cells to the peripheral blood prior to collection


peripherally acting μ-opioid receptor antagonist
alvimopan (EnteregR)
Acceleration of the time to gastrointestinal recovery following bowel surgery


methylnaltrexone (RelistorR)

Treatment of opioid-induced constipation
thrombopoietin receptor agonist
eltrombopag (PromactaR)





Treatment of thrombocytopenia in patients with chronic immune thrombocytopenic purpura



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