T-10 PROTOCOL

T-10 PROTOCOL is the chemotherapy regime for Osteosarcoma.

M high DOSE methotrexate
O Oncovin
A .. Actinomycin D
B .. Bleomycin
C .. Cisplatin, Cyclophosphamide
D .. Doxorubicin

Japanese Disease

Ossification of Posterior Longitudinal Ligament or OPLL or Japanese Disease.

* MC in mid and lower cervical spine.
* causes Spinal Cord compression.
* MRI is the investigation of choice.. Low signal on all pulse sequences. On gradient echo sequences owing to magnetic susceptibility (Blooming Effect) osteophyte size may be exaggerated resulting in overestimation of canal stenosis.

MRI FEATURES OF MESIAL TEMPORAL SCLEROSIS

Mnemonic - MAFIA.

M-Mammillary body atrophy
A-Amygdala atrophy and Atrophied Hippocampus.
F- Fornix atrophy
I- ipsilateral parahippocampal white matter tract atrophy
A- atrophied or small Temporal Lobe with enlarged temporal horn.

Adrenal myelolipoma

Unilateral adrenal mass with chunky calcification and macroscopic fat, with -15 to -25 HU is suggestive of Adrenal Myelolipoma.

Fat containing Breast Lesions

Fat contained within a breast lesion points towards benign nature.

Mnemonic - HOT GaL.

Hamartoma
Oil cyst.
Traumatic Lipid cyst..fat necrosis.
Galactocele
Lipoma

Pearl Necklace gall Bladder - in Generalized form of Adenomyomatosis of Gall Bladder.

Adenomyomatosis of Gall Bladder

Focal or generalized thickening of Gall Bladder with Comet Tail artefacts
is characteristic of Adenomyomatosis Gall Bladder.
Thickenings originate from Rokistansky-Aschoff Sinuses.
Also characterized by coexistent cholesterol deposits with
their typical comet Tail artefacts and cystic intramural inclusions.
They are usually <10 HU on CT.