Medical Eponyms Letter D

42. D’Espine’s sign is breath sounds louder over C7 than adjacent lung - suggests lesion in posterior mediastinum - e.g. lymphoma - tuberculosis - etc.
43. Dacie’s syndrome is idiopathic hyperplastic enlargement of the spleen with anemia and neutropenia; progression to lymphoma in some cases.
44. Dance’s sign is empty right lower quadrant in children with ileocecal intussusception.
45. Dawson's Fingers is a MRI Brain finding seen in Multiple Sclerosis patients. The condition is the result of inflamation around long axis of medular veins. This results in a finger-like appearance of the lesions extending mainly off the ventricles within the brain. The term is named for histologist James Walker Dawson, who first defined the condition.
46. de Musset’s sign is in aortic regurgitation - head bobbing - named after 19th century French poet who had luetic aortic insufficiency.
47. de Quervain’s disease is a stenosing tenosynovitis of the thumb extensors and abductors; pain elicited with Finkelstein’s test.
48. Degos disease is malignant atrophic papulosis; multisystem lymphocytic vasculitis characterized by thrombosis primarily of cutaneous small vessels as well as small vassels in GI tract - ocular - and CNS; has characteristic porcelain white atrophic lesion.
49. Dennie’s lines are seen in atopic dermatitis - an accentuated line or fold below the margin of the lower eyelid.
50. Denver shunt is for treating refractory ascites - peritoneovenous shunt connecting peritoneum and central venous system - compare with LeVeen shunt; Denver shunt uses valve that lies within a fluid-filled - compressible silicone chamber.
51. Denver shunt is for treating refractory ascites - peritoneovenous shunt connecting peritoneum and central venous system - compare with LeVeen shunt; Denver shunt uses valve that lies within a fluid-filled - compressible silicone chamber.
52. Denys-Drash syndrome is gonadal dysgenesis (male pseudohermaphroditism) and nephropathy leading to renal failure with increased risk of Wilms’s tumor; dominant negative missense mutation of WT-1.
53. Dercum’s disease is adipositas dolorsa - condition tending to affect obese women in middle age - mostly menopausal - consisting of multiple exquisitely tender lipomas.
54. Desçemet’s membrane is membrane that forms the deepest layer of the cornea and functions as thin basement membrane for endothelium; location where copper is deposited in Wilson’s disease Kayser-Fleischer rings.
55. Destot’s sign is scrotal hematoma suggesting pelvic fracture.
56. Dimple sign is in dermatofibroma - lateral compression with thumb and index finger produces a depression - or “dimple.”
57. Dobrin’s syndrome is TINU syndrome (tubulointerstitial nephritis with uveitis) - associated with bone marrow granulomas - first described in 1975.
58. Döhle bodies are light blue-gray, basophilic, leukocyte inclusions located in the peripheral cytoplasm of neutrophils. They measure 1-3 µm in diameter. Not much is known about their formation. They are named after German pathologist, Karl Gottfried Paul Döhle (1855-1928). Döhle bodies is irregularly shaped greenish inclusions in neutrophil cytoplasm - consisting of ribosomes and/or rough ER and are seen in severe bacterial infections. They are seen in:* Burns* Infections* Physical trauma* Neoplastic diseases* Wissler’s disease, May-Hegglin’s anomaly* Chédiak-Steinbrinck-Higashi’s syndrome.
59. Doi’s sign is elicitation of diminished deep tendon reflexes after maximal voluntary contraction in Lambert-Eaton syndrome.
60. Dorello’s canal is location where the sixth nerve penetrates the dura - an area where the nerve is liable to injury.
61. Dressler’s beat is fusion beat seen in ventricular tachycardia.
62. Drummond - marginal artery of is vessel which lies along mesenteric border of colon and supplies vasa recta; arises from right and left branches of middle colic artery and left and right colic arteries; also supplies collateral connection between superior and inferior mesenteric arteries.
63. Dubin-Johnson syndrome is mostly conjugated hyperbilirubinemia from defect in transport of bilirubin and other organic anions across the canaliculus; other liver function tests normal; accumulation of dark pigment in liver lysosomes.
64. Duffy blood group system is named after Mr. Duffy - a patient with hemophilia in whom anti-Fya was discovered by Cutbush in 1950; abbreviation Fy used because “Du” had already been taken; Fy6 antigen is the receptor for Plasmodium vivax.
65. Duncan’s disease is X-linked lymphoproliferative syndrome - normal response to childhood infections but develop fatal lymphoproliferative disorders after infection with EBV; most patients with this syndrome die of infectious mononucleosis.