Medical Eponyms Letter I

161. Imerslund-Grasbeck syndrome is juvenile megaloblastic anemia - an autosomal recessive condition involving mutation in cubulin - receptor that binds IF-B12 complex; also associated with proteinuria.
162. Isaacs’s syndrome is neuromyotonia; continuous muscle stiffness - rippling muscle movements (myokymia) - delayed relaxation following muscle contraction believed to be due to autoantibodies to presynaptic potassium channels.