Medical Eponyms Letter N

276. Nägele’s rule is means of estimating date of delivery by counting back 3 months from the first day of the last menstrual period and adding seven days; full term 38 weeks after fertilization - 40 weeks after LNMP.
277. Naxos disease is initially described on Greek island of Naxos - synrome of arrhythmogenic right ventricular cardiomyopathy - non-epidermolytic palmoplantar keratoderma - and woolly hair - due to deletion in plakoglobin - protein in adherens and desmosomal junctions.
278. Neuberg Ester is Fructose-6-Phosphate.
279. Nijmegen breakage syndrome is primary immunodeficiency autosomal recessive disorder that presents as microcephaly - a distinctive “bird-like” facies - growth retardation - recurrent pulmonary infections - chromosomal instability - radiation hypersensitivity - and increased incidence of malignancies - especially lymphomas from mutation in nibrin protein - a protein involved in DNA repair; cellular defect similar to ataxia-telangiectasia.
280. Nissen fundoplication is for treating gastroesophageal reflux disease - surrounding lower end of esophagus with cuff of gastric fundal muscle to increase lower esophageal sphincter competence.
281. Nothnagel’s syndrome is injury to superior cerebellar peduncle causing ipsilateral oculomotor palsy and contralateral cerebellar ataxia.