Newer Medicines 3: 31-41

31. Omapatrilat: Inhibits both ACE and Neutral Endopeptidase.

32. Pegaptanib: is a selective vascular endothelial growth factor (VEGF) antagonist, is indicated for the treatment of neovascular (wet) age-related macular degeneration.

33. Pemetrexed is a chemotherapy drug that interferes with three folic acid related enzymes (an antifolate antineoplastic agent), is indicated, in combination with Cisplatin, for the treatment of malignant pleural mesothelioma whose disease is unresectable or who are otherwise not candidates for curative surgery.

34. Perhexiline: pFOX (Fatty acid oxidase) inhibitor.

35. Raltegravir – is the first integrase inhibitor for drug resistant HIV infection.

36. Rifaximin - treatment of travelers’ diarrhea caused by noninvasive strains of Escherichia coli in patients 12 years old and older.

37. Sorafenib is a multikinase inhibitor targeting a number of serine/threonine and receptor tyrosine kinases, is specifically indicated for the treatment of advanced renal cell carcinoma (RCC).

38. Tezosentan: Endothelin-1-Antagonist, Cardiac remodeling inhibitor.

39. Tipranavir is a non-peptide protease inhibitor which selectively inhibits virus-specific processing of viral Gag and Gag-pol polyproteins, preventing formation of functional mature virions.

40. Ularitide: Recombinant Urodilantin, a natriuretic peptide similar to ANP, BNP.

41. Zoledronic Acid: First one yearly therapy for Osteoporosis, for Paget’s disease and post-menopausal osteoporosis.


pgmeedoubts@gmail.com