Recommendations for Treatment of NSAID-Related Mucosal Injury

Recommendations for Treatment of NSAID-Related Mucosal Injury

Clinical Setting Recommendation Active ulcer NSAID discontinued H2 receptor antagonist or PPI NSAID continued PPI Prophylactic therapy Misoprostol PPI Selective COX-2 inhibitor H. pylori infection Eradication if active ulcer present or there is a past history of peptic ulcer disease